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Rosenthal, Joshua

One or more keywords matched the following properties of Rosenthal, Joshua

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overview	Dr. Joshua Rosenthal is an assistant professor at the Institute of Neurobiogy, part of the University of Puerto Rico’s Medical Sciences Campus. His research focuses on the process of RNA editing and how it recodes key molecules in the nervous system. Current projects look at how editing changes the properties of ion pumps and voltage-dependent ion channels and examine how the editing enzymes themselves target their mRNA substrates. Dr. Rosenthal received a bachelor’s degree in biology from Haverford College. He received a Ph.D. in Biology from Stanford University with Dr. William Gilly as a mentor. He then went on to complete postdoctoral training at UCLA with Dr. Francisco Bezanilla. He has over twenty publications in scientific journals and has been supported by both the National Institute of Health and the National Science Foundation. Dr. Rosenthal’s research has been conducted at diverse sites including Chile, California, Venezuela, Baja California, Newfoundland, Scotland, the Svalbard archipelago and Antarctica.

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overview

Dr. Joshua Rosenthal is an assistant professor at the Institute of Neurobiogy, part of the University of Puerto Rico’s Medical Sciences Campus. His research focuses on the process of RNA editing and how it recodes key molecules in the nervous system. Current projects look at how editing changes the properties of ion pumps and voltage-dependent ion channels and examine how the editing enzymes themselves target their mRNA substrates. Dr. Rosenthal received a bachelor’s degree in biology from Haverford College. He received a Ph.D. in Biology from Stanford University with Dr. William Gilly as a mentor. He then went on to complete postdoctoral training at UCLA with Dr. Francisco Bezanilla. He has over twenty publications in scientific journals and has been supported by both the National Institute of Health and the National Science Foundation. Dr. Rosenthal’s research has been conducted at diverse sites including Chile, California, Venezuela, Baja California, Newfoundland, Scotland, the Svalbard archipelago and Antarctica.

One or more keywords matched the following items that are connected to Rosenthal, Joshua

Item Type	Name
Academic Article	Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing.
Concept	RNA Editing
Academic Article	Extensive editing of mRNAs for the squid delayed rectifier K+ channel regulates subunit tetramerization.
Academic Article	Identified ion channels in the squid nervous system.
Academic Article	Control of human potassium channel inactivation by editing of a small mRNA hairpin.
Academic Article	Purification and assay of ADAR activity.
Academic Article	An accurate fluorescent assay for quantifying the extent of RNA editing.
Academic Article	An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme.
Academic Article	Editing of human K(V)1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity.
Academic Article	RNA editing underlies temperature adaptation in K+ channels from polar octopuses.
Academic Article	Regulation of Na+/K+ ATPase transport velocity by RNA editing.
Academic Article	Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects.
Academic Article	Extra double-stranded RNA binding domain (dsRBD) in a squid RNA editing enzyme confers resistance to high salt environment.
Academic Article	A-to-I RNA editing: effects on proteins key to neural excitability.
Academic Article	A role for A-to-I RNA editing in temperature adaptation.
Academic Article	The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing.
Academic Article	The emerging role of RNA editing in plasticity.
Academic Article	Regulation of Ion Channel and Transporter Function Through RNA Editing.
Academic Article	An efficient system for selectively altering genetic information within mRNAs.
Academic Article	Mutations underlying Episodic Ataxia type-1 antagonize Kv1.1 RNA editing.
Academic Article	Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods.
Academic Article	Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.
Academic Article	Current strategies for Site-Directed RNA Editing using ADARs.
Academic Article	Spatially regulated editing of genetic information within a neuron.
Academic Article	A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla.
Academic Article	Adaptive Proteome Diversification by Nonsynonymous A-to-I RNA Editing in Coleoid Cephalopods.
Academic Article	In vitro and in cellula site-directed RNA editing using the ?NDD-BoxB system.
Academic Article	Site-directed A ? I RNA editing as a therapeutic tool: moving beyond genetic mutations.
Academic Article	Extensive Recoding of the Neural Proteome in Cephalopods by RNA Editing.
Academic Article	Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing.
Academic Article	Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Academic Article	High-level RNA editing diversifies the coleoid cephalopod brain proteome.

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RNA Editing